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Pituitary Radiosurgery Appointment
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JOHNS HOPKINS
Pituitary
Radiosurgery
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Pituitary
Tumor Appointments Newsletter Homepage Refer This Site
Pituitary News Glossary Cushing's Disease Prolactinoma
Johns Hopkins
Pituitary Gland Tumor / Pituitary Adenoma
Radiosurgery
Email Dr. Jeffery Williams
(jw@jhu.edu). For pituitary gland tumors including pituitary adenoma,
prolactinoma and Cushings disease, the decisions related to treatment for the
pituitary gland tumors depend upon the complete understanding of the competing
risks vs. benefits for the different treatments. Options for pituitary gland
tumor treatments may include surgery or radiosurgery. The FSR (fractionated stereotactic radiosurgery) for
pituitary tumors is an important option for treatment. The important
considerations include the size and rate of growth of the pituitary tumor as
well as the progression of any symptoms.
Curriculum
Vitae: Dr. Jeffery Williams
Director, Brain Tumor Radiosurgery
The Johns Hopkins Hospital
Board Certified: Neurological Surgery
Board Certified: Radiation Oncology
Email Dr. Jeffery
Williams.
Email Address: jw@jhu.edu
Phone: 410-614-2886
Fax: 410-614-2982
Pituitary Adenoma On-Line Consultation
- Pituitary tumors can be
treated with surgery, radiotherapy, radiosurgery and/or medications.
- For On-Line
Consultation for pituitary gland tumors please complete and send the Patient and Tumor Info and email Dr. Williams jw@jhu.edu.
The Pituitary Tumor Mailing List
Pituitary Adenoma Topics
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Pituitary Adenomas
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Pituitary adenomas cause specific clinical syndromes.
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Pituitary adenomas have specific
signs and symptoms that are primarily related to the endocrinopathies produced
by hypersecretion.
- The prolactin-secreting pituitary adenomas are the most common, and account
for approximately 30% of all pituitary tumors. The clinical findings are
galactorrhea and reproductive dysfunction.
- The endocrinopathy of excess growth hormone results in enlargement of the
extremities, face and the soft tissues, producing a characteristic appearance
called acromegaly. Acromegaly can be associated with hypertension, diabetes
mellitus and cardiovascular disease. Further, acromegaly is associated with
decreased life expectancy.
- Cushing's syndrome results from hypercortisolism and is characterized by
distinctive clinical features. Patients may develop obesity, hirsutism
(abnormal hair distribution), purple striae (stripes) on the skin, mental
problems, poor wound healing and muscle wasting.
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Microsurgical resection of pituitary adenomas can be done via two
approaches.
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Microsurgical
resection of pituitary adenomas can be done via two approaches.
- The transphenoidal approach allows resection of small to
medium-sized tumors. The risks of surgery include CSF (spinal fluid leak) and
meningitis. The rates of these complications are low, however.
- The pterional approach allows greater visualization and exposure of
larger pituitary adenomas.
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Stereotactic Radiosurgery offers non-invasive control of newly diagnosed or
recurrent pituitary tumors.
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Stereotactic
Radiosurgery allows specific irradiation of only the pituitary tumor. Narrow
beams of radiation specifically target only the pituitary tumor. The normal
brain is spared and does not receive significant exposure. For treatment there
are no "pins" placed in the scalp as with single fraction techniques. The
treatment results in control of the majority of tumors and their
endocrinological sequelae. Stereotactic radiosurgery may be particularly
suitable for functional pituitary adenomas (Cushing's disease, Acromegaly) to
reduce the level of hormonal secretion. For recurrent pituitary adenomas after
conventional surgery and radiation, stereotactic radiosurgery is particularly
appropriate, allowing sparing of the optic nerves with delivery of high
radiation dose to the recurrent pituitary adenoma.
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The patient information may be submitted.
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Stereotactic
Radiosurgery offers specific, local treatment to the pituitary adenoma with
sparing of surrounding normal tissues. The stereotactic radiosurgery is most often used for recurrent pituitary adenomas that have returned after prior surgery. The options for radiosurgery include the single session technique versus the fractionated stereotactic radiosurgery (FSR). How close the optic nerve(s) are to the pituitary tumor determines if single session or fractionated stereotactic radiosurgery is safer. The form below may be used to relay the important information regarding the pituitary tumor if helpful to the patient.
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Pituitary
Tumor Appointments Newsletter Homepage Refer This Site
Pituitary News Glossary Cushing's Disease Prolactinoma
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